Highest Short Interest Penny Stocks

Penny stocks under $5 ranked purely by short float percentage — the most heavily shorted names with the most potential squeeze fuel. Filtered to names with at least 20% short interest and a viable technical setup (Coiled or Igniting) so the list excludes outright falling knives.

Our screener flagged 25 highest short interest penny stocks in the current session, ranked by ranked by short float percentage with viable technical setup. Leading the list is Prime Medicine, Inc. Common Stock (PRME) with 46.6% short float, 11.3 days-to-cover, readiness score of 68, in the “Coiled” phase. Also worth attention: Inhibikase Therapeutics, Inc. Common Stock (IKT). The complete ranked list is below.

Data as of 2026-07-04 · End-of-day prices
#SymbolCompanyPriceMkt CapShort FloatDTCReadinessSetup
1PRMEPrime Medicine, Inc. Common Stock$3.8700666.5M46.6%11.368Coiled
2IKTInhibikase Therapeutics, Inc. Common Stock$1.9900268.0M45.0%34.470Coiled
3RXRXRecursion Pharmaceuticals, Inc. Class A Common Stock$3.80001.95B44.9%8.460Coiled
4ALTAltimmune, Inc. Common Stock$3.1600591.2M40.2%14.666Igniting
5SRFMSurf Air Mobility Inc.$1.0400128.8M37.2%3.570Coiled
6CMPXCompass Therapeutics, Inc. Common Stock$2.2700394.4M33.6%9.569Igniting
7RZLVRezolve AI PLC Ordinary Shares$2.84001.26B32.2%3.167Coiled
8HURATuHURA Biosciences, Inc. Common Stock$2.4400149.0M32.0%16.677Igniting
9INDIindie Semiconductor, Inc. Class A Common Stock$4.3300948.7M30.6%12.176Igniting
10CCCCC4 Therapeutics, Inc.$4.3000516.3M29.6%9.567Coiled
11ALLOAllogene Therapeutics, Inc. Common Stock$2.0800717.9M28.3%6.258Coiled
12FLWS1-800-FLOWERS.COM Inc$3.8500223.1M27.8%22.868Coiled
13IOVAIovance Biotherapeutics, Inc. Common Stock$4.31001.86B27.0%7.965Coiled
14VSTMVerastem, Inc.$4.5000335.7M26.6%8.969Coiled
15GOSSGossamer Bio, Inc. Common Stock$0.173280.5M26.3%3.460Coiled
16RCKTRocket Pharmaceuticals, Inc. Common Stock$3.8400373.4M26.1%8.470Coiled
17SANASana Biotechnology, Inc. Common Stock$4.0100971.2M25.8%11.175Coiled
18DFDVDeFi Development Corp. Common Stock$3.300088.5M25.2%5.165Coiled
19CRDFCardiff Oncology, Inc. Common Stock$1.270088.9M25.1%8.051Coiled
20CABACabaletta Bio, Inc. Common Stock$3.1900507.1M24.9%7.561Coiled
21LDIloanDepot, Inc.$1.2300678.0M23.4%9.960Coiled
22PACBPacific Biosciences of California, Inc.$1.6800521.8M23.3%10.257Coiled
23GRCEGrace Therapeutics, Inc. Common Stock$2.370036.9M22.9%7.066Coiled
24OGENOragenics Inc.$0.58502.6M22.8%13.059Coiled
25WOOFPetco Health and Wellness Company, Inc. Class A Common Stock$2.6200776.7M22.7%5.856Coiled

Short Float vs. Squeeze Readiness

Short float percentage is the rawest measure of squeeze potential: it's the percent of the public float that's currently sold short. A stock with 35% short float has twice as much latent squeeze fuel as one with 17%, all else being equal. But raw short interest doesn't tell you when the squeeze will fire — that's what our composite readiness score on the main squeeze scan tries to capture.

Use this list when you want to find the most heavily shorted names regardless of timing, and use the readiness-ranked list when you want trade setups that are firing now.

Key columns:

  • Short Float: percent of the public float held short. Higher = more fuel.
  • DTC (Days to Cover): at average daily volume, how many days shorts would need to exit. >3 days means shorts can't quietly cover.
  • Readiness: our composite score blending short pressure, technical setup, and momentum. Useful as a secondary filter.
  • Setup: phase of the technical setup. Coiled and Igniting are the asymmetric phases.

See also: full short squeeze list, nano-cap squeeze candidates, top bullish penny stocks.

Indicators Used in This Scan

Short Float % is the percent of a company's free-tradeable float that's currently sold short. Higher short float means more shares that must eventually be bought back — more potential squeeze fuel. Above 20% is elevated; above 30% is unusually high. The short interest is reported by FINRA and updated bi-monthly.

Days to Cover (DTC) divides the total short interest by the average daily trading volume — an estimate of how many normal trading days shorts would need to exit their positions. DTC above 3 means shorts can't quietly cover on average volume; DTC above 7 means a forced unwind has to push price meaningfully higher to find liquidity.

TTM Squeeze identifies low-volatility periods by detecting when Bollinger Bands contract inside Keltner Channels. The squeeze itself doesn't predict direction — only that volatility expansion is coming — but the accompanying momentum histogram indicates the likely direction of the eventual release. Combine a positive squeeze with positive momentum for high-conviction bullish setups.