Pre-Market Penny Stock Movers

Today's biggest pre-market penny stocks (under $5): top gainers, biggest losers, most active, and unusual-volume names before the regular session opens. Pre-market action often telegraphs where momentum is concentrated at the open.

Session: PRE · Last updated: 5/20/2026 1:36:22 PM

Top Gainers

#SymbolCompanyPriceChg %Volume
1CAPSCapstone Holding Corp. Common Stock$0.408045.20%61.6M
2PHGEBiomX Inc.$0.526040.64%82.2M
3PETZTDH Holdings, Inc. Common Shares$1.081039.51%10.5M
4WGRXWellgistics Health, Inc. Common Stock$0.220031.01%28.3M
5RKDAArcadia Biosciences, Inc.$1.115022.96%24.0M
6GCDTGreen Circle Decarbonize Technology Limited$0.700015.61%31K
7GCTSGCT Semiconductor Holding, Inc.$3.253015.36%2.5M
8JELDJELD-WEN Holding, Inc.$1.610911.19%7K
9HYFTMindWalk Holdings Corp. Common Stock$1.396011.11%135K
10ZHZhihu Inc. American Depositary Shares, each representing three (3) Class A Ordinary Shares$3.35008.41%22
11NMGNouveau Monde Graphite Inc.$1.98108.07%43K
12AVDAmerican Vanguard Corporation$2.91976.74%10K
13AMCAMC ENTERTAINMENT HOLDINGS, INC.$1.43906.62%852K
14DDCDDC Enterprise Limited$1.19006.25%608
15SMWBSimilarweb Ltd.$3.86005.98%34K
16ACHAccendra Health, Inc.$2.95005.36%186
17CXAICXApp Inc. Class A Common Stock$0.18005.20%3.2M
18RLXRLX Technology Inc. American Depositary Shares, each representing the right to receive one (1) Class A ordinary share$2.19504.76%344K
19WRNWestern Copper and Gold Corporation$2.70004.56%5K
20ODVOsisko Development Corp.$2.99004.55%6K

Top Losers

#SymbolCompanyPriceChg %Volume
1RUBIRubico Inc. Common Stock$0.9130-33.60%1.9M
2PPBTPurple Biotech Ltd. American Depositary Shares$2.7530-15.70%5.8M
3SUGPSU Group Holdings Limited Class A Ordinary Shares$4.4930-15.60%1.5M
4CPHIChina Pharma Holdings, Inc.$0.6810-12.90%5K
5MTNBMatinas BioPharma Holdings, Inc.$0.4998-12.80%53K
6DXFEason Technology Limited American Depositary Shares (each representing sixty-thousand (60,000) Ordinary Shares)$0.9330-10.90%38K
7LUDLuda Technology Group Limited$4.8000-10.50%5K
8AIMAIM ImmunoTech Inc.$0.3701-9.15%887K
9AMBOAmbow Education Holding Ltd. American Depository Shares (each representing twenty (20) Class A Ordinary Shares)$2.6000-8.77%2K
10PWPower REIT$0.5401-8.11%3K
11VTAKCatheter Precision, Inc.$0.7400-8.02%46K
12ANVSAnnovis Bio, Inc.$1.7900-7.22%268K
13APUSApimeds Pharmaceuticals US, Inc.$1.3200-7.04%4
14AMSTAmesite Inc.$1.6310-6.94%1.6M
15ZDGEZedge, Inc.$2.8100-6.33%205
16REEDReed's, Inc.$1.9170-6.28%3K
17NXXTNextNRG, Inc. Common Stock$0.7380-6.11%12.2M
18AUUDAuddia Inc. Common Stock$1.4660-5.62%392K
19MITQMoving iMage Technologies, Inc.$0.5844-5.28%1K
20GBRNew Concept Energy Inc$0.7604-4.71%1K

Most Active

#SymbolCompanyPriceChg %Volume
1SLXNSilexion Therapeutics Corp Ordinary Shares$0.62600.00%163.3M
2JUNSJupiter Neurosciences, Inc. Common Stock$0.51000.00%123.4M
3SDMSmart Digital Group Limited Ordinary Shares$1.88000.00%25.9M
4PHGEBiomX Inc.$0.526040.64%82.2M
5GCLGCL Global Holdings Ltd Ordinary Shares$0.73900.00%42.1M
6RKDAArcadia Biosciences, Inc.$1.115022.96%24.0M
7WOKWORK Medical Technology Group LTD Class A Ordinary Shares$0.2300-3.02%113.6M
8CAPSCapstone Holding Corp. Common Stock$0.408045.20%61.6M
9AMPGAMPLITECH GROUP INC. COM$4.53100.00%4.4M
10GDCGD Culture Group Limited Common Stock$0.14700.00%109.5M
11PPBTPurple Biotech Ltd. American Depositary Shares$2.7530-15.70%5.8M
12MEHAFunctional Brands, Inc. Common Stock$0.08340.00%164.5M
13PETZTDH Holdings, Inc. Common Shares$1.081039.51%10.5M
14NXXTNextNRG, Inc. Common Stock$0.7380-6.11%12.2M
15GCTSGCT Semiconductor Holding, Inc.$3.253015.36%2.5M
16MTVAMetaVia Inc. Common Stock$1.97504.26%3.7M
17PLUGPlug Power Inc.$3.37401.51%2.1M
18SUGPSU Group Holdings Limited Class A Ordinary Shares$4.4930-15.60%1.5M
19WGRXWellgistics Health, Inc. Common Stock$0.220031.01%28.3M
20TDICDreamland Limited Class A Ordinary Shares$0.63500.00%9.1M

Unusual Volume

#SymbolCompanyPriceChg %VolumeVol Ratio
1PHGEBiomX Inc.$0.526040.64%82.2M2931.56x
2RKDAArcadia Biosciences, Inc.$1.115022.96%24.0M1399.17x
3CAPSCapstone Holding Corp. Common Stock$0.408045.20%61.6M506.35x
4MTVAMetaVia Inc. Common Stock$1.97504.26%3.7M386.51x
5AMSTAmesite Inc.$1.6310-6.94%1.6M303.45x
6SNALSnail, Inc. Class A Common Stock$1.0800-3.57%285K107.18x
7NXXTNextNRG, Inc. Common Stock$0.7380-6.11%12.2M67.35x
8PMIPicard Medical, Inc.$0.1570-1.41%1.8M30.84x
9WGRXWellgistics Health, Inc. Common Stock$0.220031.01%28.3M25.11x
10MTNBMatinas BioPharma Holdings, Inc.$0.4998-12.80%53K16.12x
11EEXEmerald Holding, Inc.$5.10002.00%1615.11x
12HCWBHCW Biologics Inc. Common Stock$1.0470-3.77%869K11.50x
13GCTSGCT Semiconductor Holding, Inc.$3.253015.36%2.5M11.28x
14AMSAmerican Shared Hospital Services$1.36801.49%32311.04x
15ANVSAnnovis Bio, Inc.$1.7900-7.22%268K9.78x
16PWPower REIT$0.5401-8.11%3K6.52x
17BNZIBanzai International, Inc. Class A Common Stock$3.42303.68%626K6.15x
18MLSSMilestone Scientific, Inc. Common Stock$0.3452-0.52%2K5.25x
19CLDICalidi Biotherapeutics, Inc.$0.1844-1.63%111K4.57x
20AMZEAmaze Holdings, Inc.$0.1280-0.85%802K4.45x

Why Pre-Market Penny Stocks Matter

Pre-market trading (roughly 4:00 AM - 9:30 AM ET) is thinner than regular hours, but for penny stocks it's often where the day's narrative gets set. A penny stock gapping up 30% pre-market on news will typically see continued momentum or a sharp fade once the open liquidity arrives — both setups offer trade structure.

Things to weigh when looking at pre-market movers:

  • Volume: a 50% pre-market gain on 20,000 shares is noise; the same gain on 2M shares is real interest.
  • Catalyst: is there an 8-K, earnings, or news item driving it, or is it untethered?
  • Float: low-float names amplify both the rip and the fade.
  • Prior-day close: a stock gapping from $1.20 to $1.80 has very different implications than $0.20 to $0.80.

See also: after-hours penny stocks, full-session movers, short squeeze candidates.